Melanoma — Epidemiology, Genetics and Risk Factors

Short Report Risk of Melanoma among Radiologic Technologists in the United States

D. Michal FREEDMAN*, Alice SIGURDSON, R. Sowmya RAO, Michael HAUPTMANN, Bruce ALEXANDER, Aparna MOHAN, Michele MORIN DOODY and Martha S. LINET Division of Cancer Epidemiology and Genetics, Radiation Epidemiology Branch, National Cancer Institute, Bethesda, MD, USA Division of Cancer Epidemiology and Genetics, Biostatistics Branch, National Cancer Institute, Bethesda, MD, USA Division of Environ...

Melanoma Epidemiology and Prevention.

The epidemiology of melanoma is complex, and individual risk depends on sun exposure, host factors, and genetic factors, and in their interactions as well. Sun exposure can be classified as intermittent, chronic, or cumulative (overall) exposure, and each appears to have a different effect on type of melanoma. Other environmental factors, such as chemical exposures-either through occupation, at...

The value of small observations in the era of big science.

We are now unequivocally in the era of big science. Genotyping costs have become so trivial and genetic variation is so important that it is almost heresy to consider launching an epidemiologic investigation without collecting germ line DNA to evaluate the contributions of genetic diversity to the pathogenesis of disease. As genetics steps into the spotlight of epidemiology, studies are burstin...

From Melanocyte to Metastatic Malignant Melanoma

Malignant melanoma is one of the most aggressive malignancies in human and is responsible for almost 60% of lethal skin tumors. Its incidence has been increasing in white population in the past two decades. There is a complex interaction of environmental (exogenous) and endogenous, including genetic, risk factors in developing malignant melanoma. 8-12% of familial melanomas occur in a familial ...

Melanoma Epidemiology, Risk Factors, and Clinical Phenotypes